“A typical human mouth teems with as many as 700 different species of microbes. A handful of these have been specifically implicated in promoting gum disease, dental cavities, and bad breath, but for the most part, the make-up of this complex ecosystem and its impact on human health remain largely unexplored. A new device created by…researchers, however, may make some of the most reclusive members of this and other microscopic communities much more accessible for laboratory study.

The vast majority of microbes are notoriously resistant to growing in laboratory cultures because they are so intricately linked to their own unique ecosystems…The microfluidic chip designed…for the current study is equipped with tiny chambers and valves that allow researchers to isolate microbes at the nanoliter scale. Because each microbe is isolated in a vanishingly small volume of liquid, the concentration of its genetic material within that solution is actually quite high…” Full Slice

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