Lots in this one and well worth follow up

“…The study was so comprehensive that the team could see signatures of an undiscovered system of DNA repair, reducing the mutations in highly active genes, suggesting the genome seeks to preserve these regions above many others.

However, as previous studies suggested, there was not one mutation that stood out as ‘the lung cancer gene’. One gene - CHD7 - was found to be mutated in several SCLC samples. This gene is part of an emerging pattern that cancers often contain mutations in genes that are generalists in regulating genetic activity alongside more specific changes….” Full Slice

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