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Shape shifting proteins

June 20th, 2009 by SecureCare

“…a protein dimer made up of two identical parts can actually twist itself so that one copy of the protein is turned upside down if its environment is only slightly altered…”We were able to easily switch A2L2 from an inactive state to one that could bind RNA, and it takes only quite mild changes in conditions to make this change. These direct observations show that this protein dimer has two native structures available to it, and that minor perturbations can cause this balance to be altered,”…” Full Slice

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